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Spectrophotometric, chemometric and chromatographic determination of naphazoline hydrochloride and chlorpheniramine maleate in the presence of naphazoline hydrochloride alkaline degradation product

✍ Scribed by Sayed, Nour el deen; Hegazy, Maha; Abdelkawy, Mohammed; Abdelfatah, Rehab


Book ID
120200433
Publisher
Egypts Presidential Specialized Council for Education and Scientific Research
Year
2013
Tongue
English
Weight
605 KB
Volume
51
Category
Article
ISSN
1110-0931

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## Abstract Two sensitive and reproducible methods are described for the quantitative determination of itopride hydrochloride (IH) in the presence of its degradation products. The first method is based on HPLC separation on a reversed phase Kromasil column [C~18~ (5‐μm, 25 cmΓ—4.6 mm, ID)] at ambien