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Spectroelectrochemistry of 1,4-naphthoquinones and 5-nitroindazoles: Reduction mechanisms and free radical stability

✍ Scribed by Pozo, B.; Aguilera-Venegas, B.; Olea-Azar, C.; Arán, V.J.; Salas, C.O.; Zúñiga, M.C.


Book ID
122095386
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
73 KB
Volume
65
Category
Article
ISSN
0891-5849

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Mechanisms of toxicity of 2- and 5-hydro
✍ Mary D'Arcy Doherty; Adrian Rodgers; Gerald M. Cohen 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 569 KB

The mechanisms of toxicity to isolated rat hepatocytes of two structurally related naphthoquinones have been studied. Both 5-OH-1,4-naphthoquinone (5-OH-1,4-NQ; juglone) and 2-OH-1,4-naphthoquinone (2-OH-1,4-NQ; lawsone) caused a concentration-dependent cytotoxicity to hepatocytes which was preceded