Spectral characteristics of early receptor potential in congenital red-green color blindness
✍ Scribed by Jhoji Tanabe; Hirohiko Nakazato; Hisayoshi Tanabe; Hidetoshi Hanasaki; Kazuo Kawasaki; Daizo Yonemura
- Book ID
- 104647500
- Publisher
- Springer-Verlag
- Year
- 1986
- Tongue
- English
- Weight
- 354 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0012-4486
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✦ Synopsis
The spectral response curve (amplitude versus wavelength) of the R 2 of the early receptor potential (ERP) was studied in normal, protan, and deutan subjects. The R 2 amplitude peaked at 520nm in most normal subjects. The R 2 at long wavelengths was smaller than normal in protans and larger than normal in deutans when the maximum amplitudes were normalized to 100% at the peak. The ratio of the R 2 amplitude at 460nm to that at 600nm clearly differed between protans and deutans. The ERP and the rapid off-response, which is mainly due to the cessation of the late receptor potential, were recorded in the same subjects. The ratio of the sensitivity of the rapid oft-response at 500 nm to that at 600 nm was correlated with the ratio of the R 2 amplitude at 460nm to that at 600nm (correlation coefficient, 0.823, p < 0.001). This study, in conjunction with our previous study, indicates that the abnormality is in the outer segments of the cones in protans and deutans.