SPECT/CT for sentinel lymph node mapping in head and neck melanoma
✍ Scribed by Lenka Vermeeren; Renato A. Valdés Olmos; W. Martin C. Klop; Iris M. C. van der Ploeg; Omgo E. Nieweg; Alfons J. M. Balm; Michiel W. M. van den Brekel
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 225 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background.
The additional value of single photon emission computed tomography with CT (SPECT/CT) for detection and localization of sentinel nodes in patients with a melanoma of the head and neck was determined.
Methods.
Thirty‐eight patients received conventional lymphoscintigraphy followed by hybrid SPECT/CT. The number of sentinel nodes visualized and anatomic information provided were analyzed. Changes in surgical approach due to additional information from the SPECT/CT were evaluated in 20 patients.
Results.
SPECT/CT visualized a mean of 2.6 sentinel nodes per patient (range, 1–6). SPECT/CT depicted an additional sentinel node in 16% of the patients and clearly showed the anatomic location of the hot nodes in all patients. The surgical approach was adjusted on the basis of SPECT/CT images in 11 patients (55%).
Conclusion.
SPECT/CT visualizes more sentinel nodes than conventional images and shows their anatomic location. SPECT/CT is recommended in patients with a melanoma in the head or neck. © 2010 Wiley Periodicals, Inc. Head Neck, 2011
📜 SIMILAR VOLUMES
## Abstract ## Background Current therapy for intermediate thickness melanoma involves wide local excision with sentinel lymph node biopsy (SLNB). SLNB provides important prognostic information and immediate regional lymphadenectomy for a positive sentinel lymph node (SLN) may improve survival and
Background. Lymphatic drainage in the head and neck region is known to be particularly complex. This study explores the value of sentinel node biopsy for melanoma in the head and neck region. Methods. Thirty consecutive patients with clinically localized cutaneous melanoma in the head and neck regi