Specificity space, the structure and evolution of metabolic pathways: Part II of a general theory

✍ Scribed by Rein Kilkson

• Publisher: Springer Netherlands
• Year: 1989
• Tongue: English
• Weight: 292 KB
• Volume: 17
• Category: Article
• ISSN: 0092-0606
• DOI: 10.1007/bf00417751

✦ Synopsis

Biomolecular structures are interacting in terms of their force fields. These force fields define the specificity surfaces of the molecules. Specificity surfaces are represented by specificity vectors in a multidimensional specificity space. A quantitative analytical expression is developed for biochemical reactions and the evolution of metabolic pathways in the specificity space. This leads to detailed identification of various biomolecular processes with individual terms in the equation. This theoretical analysis permits defining detailed function and resolution requirements of enzymes, as well as, how these fit into the overall metabolic pattern of the cell. This paper is Part II of a general theory of the physical basis of the biological state of matter.