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Specificity of arachidonic acid-induced inhibition of growth and activation of c-jun kinases and p38 mitogen-activated protein kinase in hematopoietic cells

✍ Scribed by Maria Teresa Rizzo; Nancy Pudlo; Lindsey Farrell; Anne Leaver


Book ID
117841338
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
384 KB
Volume
66
Category
Article
ISSN
0952-3278

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## Abstract 8‐Cl‐cAMP (8‐chloro‐cyclic AMP), which induces differentiation, growth inhibition and apoptosis in various cancer cells, has been investigated as a putative anti‐cancer drug. Although we reported that 8‐Cl‐cAMP induces growth inhibition via p38 mitogen‐activated protein kinase (MAPK) an