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Specificity of 6-hydroxydopamine-induced destruction of mesolimbic or nigrostriatal dopamine-containing terminals

โœ Scribed by Peter H. Kelly; Eileen M. Joyce; Kenneth P. Minneman; Oliver T. Phillipson

Book ID
118863486
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
334 KB
Volume
122
Category
Article
ISSN
0006-8993

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๐Ÿ“œ SIMILAR VOLUMES

Mesolimbic dopamine neurons: Effects of
Mesolimbic dopamine neurons: Effects of 6-hydroxydopamine-induced destruction and receptor blockade on drug-induced rotation of rats
โœ P. H. Kelly; K. E. Moore ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› Springer ๐ŸŒ English โš– 654 KB

Bilateral injections of 6-hydroxydopamine (6-OHDA) into the nucleus accumbens greatly reduced the dopamine content of this nucleus and the olfactory tubercle and blocked the ipsilateral rotation induced by amphetamine and methamphetamine in rats with unilateral 6-OHDA lesions of the caudate nucleus.