Reversibility of ganglioside effects on
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A. Dekker; M. Manthorpe; S. Varon
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Article
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1990
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John Wiley and Sons
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English
โ 705 KB
The B-subunit of cholera toxin (BCT) induces a morphological change in cultured rat cerebral astrocytes from flat (epithelioid) to stellate (process-bearing). This stellation is reversed by the gangliosides GM1 and GDla at concentrations of 10 p M or higher. Upon changing to a ganglioside-free mediu