Specificities of immobilized Geotrichum candidum CMICC 335426 lipases A and B in hydrolysis and ester synthesis reactions in organic solvents

Enhancement of enantioselectivity and re

Enhancement of enantioselectivity and reaction rate on the synthesis of (S)-ketoprofen hydroxyalkyl ester in organic solvents via isopropanol-dried immobilized lipase

✍ Chun-Sheng Chang; Chin-Shuo Hsu 📂 Article 📅 2005 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 151 KB

## Abstract Lipase‐catalyzed enantioselective esterification between (__R__,__S__)‐ketoprofen and alkanediol in organic solvents was developed to produce (__S__)‐ketoprofen hydroxyalkyl esters. The acyl acceptor of 1,6‐hexanediol for the resolution of (__R__,__S__)‐ketoprofen yielded only the enant