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Specific Separation of Products in Supported Oligonucleotide Syntheses Using the Triester Method

✍ Scribed by Prof. Dr. Hartmut Seliger; Dr. Hans-Helmut Görtz


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
217 KB
Volume
20
Category
Article
ISSN
0044-8249

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✦ Synopsis


The mixture of homologous nucleotide fragments usually formed during carrier‐oligonucleotide synthesis can be separated chromatographically so as to isolate the desired fragment, if the latter is protected at the 5′‐end with a hexadecyloxytrityl group (see (2) in the previous communication).