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Specific Recognition of Disaccharides in Water by an Artificial Bicyclic Carbohydrate Receptor

✍ Scribed by Theis Reenberg; Nils Nyberg; Jens Ø. Duus; Joost L. J. van Dongen; Morten Meldal

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
263 KB
Volume
2007
Category
Article
ISSN
1434-193X

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Sequence-Dependent Binding of Dipeptides
Sequence-Dependent Binding of Dipeptides by an Artificial Receptor in Water
✍ Carsten Schmuck; Daniel Rupprecht; Wolfgang Wienand 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 306 KB

## Abstract An artificial dipeptide receptor (**1**) was designed and observed to bind the deprotonated dipeptide Ac‐D‐Ala‐D‐Ala‐OH in buffered water with __K__ = 33 100 m^−1^, whereas other dipeptides such as Ac‐Gly‐Gly‐OH or Ac‐D‐Val‐D‐Val‐OH were bound less efficiently, by factors of more than 1