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Specific organic acids enhance the D-ribose productivity of a transketolase-defective Bacillus subtilis strain

✍ Scribed by Peter De Wulf; Wim Soetaert; Dieter Schwengers; Erick J. Vandamme


Book ID
101262461
Publisher
Wiley (John Wiley & Sons)
Year
1997
Tongue
English
Weight
234 KB
Volume
70
Category
Article
ISSN
0268-2575

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✦ Synopsis


When the transketolase-defective and D-ribose-producing Bacillus subtilis strain ATCC 21951 was cultured in a medium provided with certain organic acids, a signiÐcantly enhanced D-ribose titre was obtained, while the production of acetoin and 2,3-butanediol drastically decreased. Although the biochemical background of this phenomenon is not completely understood, it makes D-ribose synthesis more efficient and cheaper, the latter due to an easier recovery of Dribose from the fermentation medium.