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Specific oligonucleotide invasion into an end of a DNA duplex

✍ Scribed by V. K. Gasanova; A. A. Neschastnova; G. A. Belitskii; M. G. Yakubovskaya

Book ID
110174308
Publisher
SP MAIK Nauka/Interperiodica
Year
2006
Tongue
English
Weight
199 KB
Volume
40
Category
Article
ISSN
0026-8933

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A 4-(3-n-butylureidophenyl)imidazole nucleoside was successfully incorporated into a triplex-forming oligonucleotide (TFO). Binding affinity and base pair selectivity of the TFO containing this non-natural nucleoside were studied with various duplex targets containing all four possible Watson-Crick