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Specific labelling of microsomal proteins by reactive intermediates generated from 2-acetylaminofluorene in vitro

✍ Scribed by Mustak Ali Kaderbhai; Tony K. Bradshaw; Robert B. Freedman


Book ID
113136274
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
853 KB
Volume
36
Category
Article
ISSN
0009-2797

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In a study designed to examine the nature of short-lived, electrophilic intermediates liberated during decomposition of N,N'-bis(2-chloroethyI)-N-nitrosourea (BCNU) in vitro and also on administration of BCNU (140 pmol i.p.) to rats in vivo, both on-line and off-line LC/MS/MS techniques were employe