Subclassification of presynaptic 5-HT au
Subclassification of presynaptic 5-HT autoreceptors in the human cerebral cortex as 5-HT1Dβreceptors
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K. Fink; M. Göthert; J. Zentner
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Article
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1995
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Springer-Verlag
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English
⚖ 410 KB
Human cerebral cortical synaptosomes were used to determine the 5-hydroxytryptamine (5-HT) receptor subtype to which the inhibitory presynaptic 5-HT autoreceptor belongs. The synaptosomes preincubated with [3H~5-HT were superfused and tritium overflow was stimulated by high K +. The K +-evoked triti