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Specific inhibition of transcription factor NF-κB through intracellular protein delivery of IκBα by the Herpes virus protein VP22

✍ Scribed by Stroh, Christopher; Held, Jürgen; Samraj, Ajoy Kumar; Schulze-Osthoff, Klaus


Book ID
110067645
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
308 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Abstract ## Objective To examine the role of interferon regulatory factor 1 (IRF‐1) in tumor necrosis factor α (TNFα)–induced interleukin‐18 binding protein a (IL‐18BPa) expression in rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods TNFα‐induced IRF‐1 expression was assessed by r