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Specific inhibition of herpesvirus ribonucleotide reductase by synthetic peptides

✍ Scribed by Dutia, Bernadette M.; Frame, Margaret C.; Subak-Sharpe, John H.; Clark, William N.; Marsden, Howard S.

Book ID
109743771
Publisher
Nature Publishing Group
Year
1986
Tongue
English
Weight
392 KB
Volume
321
Category
Article
ISSN
0028-0836

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__Chlamydia trachomatis__ ribonucleotide reductase (RNR) is a class Ic RNR. It has two homodimeric subunits: proteins R1 and R2. Class Ic protein R2 in its most active form has a manganese–iron metal cofactor, which functions in catalysis like the tyrosyl radical in classical class Ia and Ib RNRs. O