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Specific inhibition of delta antigen by in vitro system by antisense oligodeoxynucleotide: implications for translation mechanism and treatment

โœ Scribed by Trong-zong Chen; Jaw-ching Wu; Lo-chun Au; Kong-bung Choo


Book ID
114140523
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
778 KB
Volume
65
Category
Article
ISSN
0166-0934

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## Abstract ## Background Cystic fibrosis (CF) respiratory epithelia are characterized by a defect Cl^โˆ’^ secretion and an increased Na^+^ absorption through epithelial Na^+^ channels (ENaC). The present study aimed to find an effective inhibitor of human ENaC with respect to replacing amiloride th