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Specific inhibition of bcr-abl gene expression by small interfering RNA in bcr-abl+ cells

Book ID
117659817
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
148 KB
Volume
38
Category
Article
ISSN
0959-8049

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πŸ“œ SIMILAR VOLUMES

Inhibition of bcr-abl and/or c-abl gene
Inhibition of bcr-abl and/or c-abl gene expression by small interfering, double-stranded RNAs : Cross-talk with cell proliferation factors and other oncogenes
✍ Hideki Ohba; Zhivko Zhelev; Rumiana Bakalova; Ashraf Ewis; Toshiro Omori; Mitsur πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 789 KB

## Abstract ## BACKGROUND Short, 21‐mer, double‐stranded/small interfering __RNAs__ (__ds__/__siRNAs__) were designed to target __bcr__‐__abl mRNA__ in chronic myelogenous leukemia (CML) with a potential also to target __c__‐__abl__ __mRNA__. ## METHODS __ds__/__siRNAs__ were transfected into __