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Specific induction of indoleamine 2,3-dioxygenase by bacterial lipopolysaccharide in the mouse lung

โœ Scribed by Ryotaro Yoshida; Yoshihiro Urade; Koh Nakata; Yasuyoshi Watanabe; Osamu Hayaishi


Book ID
115704968
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
816 KB
Volume
212
Category
Article
ISSN
0003-9861

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๐Ÿ“œ SIMILAR VOLUMES


Lipopolysaccharide induction of indoleam
โœ Suwako Fujigaki; Kuniaki Saito; Kenji Sekikawa; Shigenobu Tone; Osamu Takikawa; ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 109 KB ๐Ÿ‘ 1 views

Indoleamine 2,3-dioxygenase (IDO) is a rate-limiting enzyme in the L-tryptophan-kynurenine pathway, which converts an essential amino acid, L-tryptophan, to N-formylkynurenine. It has been speculated that IFN-gamma is a dominant IDO inducer in vivo. The present study used IFN-gamma or TNF-alpha gene