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Specific HLA-DQB and HLA-DRB1 Alleles Confer Susceptibility to Pemphigus Vulgaris

✍ Scribed by Stephen J. Scharf, Adam Freidmann, Lawrence Steinman, Chaim Brautbar and Henry A. Erlich

Book ID
123637072
Publisher
National Academy of Sciences
Year
1989
Tongue
English
Weight
944 KB
Volume
86
Category
Article
ISSN
0027-8424

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Primary Sjogren's syndrome (1" SS) is a systemic autoimmune disease characterized by lymphocytic infiltration of the salivary glands and autoantibody production. In order to identify genetic factors that play a role in pathogenesis and predict extent of disease, we used Southern blot and polymerase