Nucleobase-derived radicals are crucial transient intermediates in the radiation damage of nucleic acids (RNA and DNA). Among the recognized mechanisms of radiation damage, capture of a low-energy electron followed by protonation of the transient anion radical results in the formation of hydrogen-at
✦ LIBER ✦
Specific Generation of 1-Methylcytosine Radicals in the Gas Phase
✍ Scribed by Chunxiang Yao; Maria L. Cuadrado-Peinado; Miroslav Polášek; František Tureček
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 120 KB
- Volume
- 117
- Category
- Article
- ISSN
- 0044-8249
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A rate constant for the epoxidation of acrolein by acetylperoxyl radicals has been determined to be k 4 ϭ (1.3 Ϯ 0.9) ϫ 10 4 dm 3 mol Ϫ1 s Ϫ1 at 383 K, which is anomalously fast in comparison with the epoxidation of alkenes. Abstraction of the acyl hydrogen atom from acrolein by acetylperoxyl radica