Specific deuteration β to a keto group: Reduction of α β-ethylenic ketones with lithium and deuterated propylamine

✍ Scribed by Marcel Fetizon; Jacques Gore

• Publisher: Elsevier Science
• Year: 1966
• Tongue: French
• Weight: 196 KB
• Volume: 7
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)72905-4

✦ Synopsis

Press Ltd. printed in Great Britain, SPECIFIC DEXITFXUTION PTOAl&TO mOUP t RFXIUCTION OF a k -cKCTONEY WITliLITHIOMANDDEDTEZA~DPROPYIAH~ Marcel FH'IZON andJacques GORE LaboratoFre de St&dochimie -Facult6 des Soienoea d'Orsay -(S et O)BRAN(X (Received 3 December 1965) Whereas the introduction of a deuterium atom a to a keto group is 8 well know-n process (for a review see ref. l), this is not the case for the position. DJERASSI and his co-workers have however described the reduction the C@ ethylenic ketone r by lithium in dsuterated liquid ammonia (2).