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Specific determination of unbound oxacillin in protein solution with cefoperazone by high-performance frontal analysis with chemiluminescence detection

โœ Scribed by Famei Li; Mingxi Qiao; Xingjie Guo

Book ID
101757299
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
80 KB
Volume
17
Category
Article
ISSN
0269-3879

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Determination of the unbound concentration of hydrophobic drugs in albumin solutions by high-performance frontal analysis using a diol-silica column
โœ Akimasa Shibukawa; Chikako Nakao; Takeshi Sawada; Akira Terakita; Noritsugu Moro ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 690 KB

High-performance frontal analysis (HPFA) using diol-silica column allows the determination of the unbound concentration of hydrophobic drugs under protein binding equilibrium, which is often difficult by the conventional methods. After the direct injection of a drug-protein mixed solution onto a dio