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Specific cutaneous involvement in Hodgkin's disease

✍ Scribed by Dr Dolors Tassies; Jorge Sierra; Emilio Montserrat; Rosa Marti; Teresa Estrach; Ciril Rozman

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 772 KB
Volume: 10
Category: Article
ISSN: 0278-0232
DOI: 10.1002/hon.2900100202

No coin nor oath required. For personal study only.

✦ Synopsis

In Hodgkin's disease (HD) specific cutaneous involvement is rare. When it occurs, retrograde lymphatic spread, direct extension from the underlying lymph nodes, and hematogenous dissemination are the mechanisms usually implicated. Among 349 patients with HD diagnosed and followed-up at our institution from 1969 to 1990, three (0.85 per cent) presented specific cutaneous involvement. In two cases with mixed cellularity subtype, skin lesions displayed histologic features similar to those found in the lymph node. Treatment with combination chemotherapy resulted in rapid disappearance of the lesions in two patients but was ineffective in the third. Previous reports of cutaneous involvement in HD, its differential diagnosis, prognostic significance, and treatment are briefly reviewed.

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