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Specific binding of 125I-labeled human recombinant IL-3 to human bone marrow and chronic myelogenous leukemia cells


Book ID
122952685
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
161 KB
Volume
1
Category
Article
ISSN
1043-4666

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Specific binding, internalization, and d
โœ Thomas G. Gesner; R. Allan Mufson; Christine R. Norton; Katherine J. Turner; Yu ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 745 KB

We have studied the interaction of 35S-labeled recombinant IL-3 with the acute myelogenous leukemia cell line, KG-1. 35S-IL-3 bound to these cells in a time dependent, saturable, and specific manner at 4OC. Scatchard transformation of binding isotherms demonstrated the existence of a small number (2