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Specific anti-fibroblast cytotoxicity of antibodies to fibroblast surface antigen

✍ Scribed by Erkki Ruoslahti; Hans O. Sjögren

Publisher
John Wiley and Sons
Year
1976
Tongue
French
Weight
276 KB
Volume
18
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

An antiserum to SF antigen was shown to be selectively cytotoxic to two human fibroblast lines, while two tumor cell lines (one melanoma and one Hela cell line) were resistant. The selective cytotoxicity was also demonstrable in mixtures of fibroblasts and tumor cells. The cytotoxic effect was abrogated by admixture of human serum containing SFA.

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