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Specific and sensitive determination of digoxin and metabolites in human serum by high performance liquid chromatography with cyclodextrin solid-phase extraction and precolumn fluorescence derivatization

✍ Scribed by M.-C. Tzou; R.A. Sams; R.H. Reuning


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
707 KB
Volume
13
Category
Article
ISSN
0731-7085

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A high-performance liquid chromatographic system, combining solid-phase extraction and automated precolumn derivatization is described for the routine determination of methotrexate in human plasma. The sample extraction and elution onto the analytical column were performed automatically and concomit