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Specific and sensitive detection of purified HLA molecules in an ELISA using mouse, rabbit and human anti-HLA antibodies

โœ Scribed by Michel Bouillot; Jeannine Choppin; Jean-Paul Levy


Book ID
118901537
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
517 KB
Volume
116
Category
Article
ISSN
0022-1759

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Among the HLA-DR-specific monoclonal antibodies (mAbs) that have been characterized previously, there is a marked shortage of DR alpha chain-specific mAbs which stain unfixed cells. This may result from the high degree of sequence similarity between the alpha 1 domains of HLA-DR and H-2E leading to