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Specific and Irreversible Cyclopeptide Inhibitors of Dipeptidyl Peptidase IV Activity of the T-Cell Activation Antigen CD26

✍ Scribed by Nguyen, Coralie; Blanco, Julià; Mazaleyrat, Jean-Paul; Krust, Bernard; Callebaut, Christian; Jacotot, Etienne; Hovanessian, Ara G.; Wakselman, Michel


Book ID
127251623
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
188 KB
Volume
41
Category
Article
ISSN
0022-2623

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CD26 expression and dipeptidyl peptidase
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The transmembrane serine aminopeptidase dipeptidyl peptidase IV (DPP IV) (also known as CD26) participates in several immunological functions and has a binding affinity for several molecules, including collagen, which may be an integral mechanism for T cells to traverse endothelial barriers. Since C