Specific and Amplified Current Responses to Histidine and Histamine Using Immobilized Copper–Monoamine Oxidase Membrane Electrode, Based on Novel Ascorbate Oxidase Activity Induced by Exogenous Ligands
✍ Scribed by Yasushi Hasebe; Seiichi Toda; Kazuo Aoki; Hiroshi Tonobe; Shunichi Uchiyama
- Book ID
- 102558910
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 137 KB
- Volume
- 251
- Category
- Article
- ISSN
- 0003-2697
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✦ Synopsis
zyme induces a conformational change in the enzyme, Upon the addition of histidine and histamine, the resulting in a change in the affinity of the substrate copper containing monoamine oxidase (MAO) cataand the rate of enzymatic reaction.
lyzes the oxidation of L-ascorbic acid (AsA) by dishand, it is well known that activities of some enzymes monoamine oxidase; SOD, superoxide dismutase; MDA, monodehy- are sometimes modified by some ligands (called allostedroascorbate radical; ASOD, ascorbate oxidase; DAsA, dehydroascor- bate.
ric effectors), and the binding of these ligands to en-32