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Species-specific modulation of the mitochondrial permeability transition by norbormide

✍ Scribed by Fernanda Ricchelli; Federica Dabbeni-Sala; Valeria Petronilli; Paolo Bernardi; Brian Hopkins; Sergio Bova


Book ID
119193101
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
219 KB
Volume
1708
Category
Article
ISSN
0005-2728

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Mitochondria of higher cells contain a channel, the permeability transition pore (PTP), that, when open, increases the permeability of the inner membrane to ions and small molecules. The PTP may be of importance in cellular calcium homeostasis and in the execution of programmed cell death, and the d