𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Species differences in the induction of drug metabolism by rifampicin

✍ Scribed by van den Broek, J. M.

Publisher
Springer
Year
1983
Tongue
Dutch
Weight
134 KB
Volume
5
Category
Article
ISSN
1573-739X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Induction of drug metabolism enzymes and
Induction of drug metabolism enzymes and transporters by oltipraz in rats
✍ Matthew D. Merrell; Lisa M. Augustine; Angela L. Slitt; Nathan J. Cherrington πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 325 KB

## Abstract Coordinate regulation of Phase‐I and ‐II enzymes with xenobiotic transporters has been shown after treatment with microsomal enzyme inducers. The chemopreventive agent oltipraz (OPZ) induces Phase‐I and ‐II drug‐metabolizing enzymes such as CYP2B and NQO1. The purpose of this study was

The species differences of intestinal dr
The species differences of intestinal drug absorption and first-pass metabolism between cynomolgus monkeys and humans
✍ Masayuki Takahashi; Takuo Washio; Norio Suzuki; Katsuhiro Igeta; Shinji Yamashit πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 200 KB

In order to elucidate the causes of the species differences in the oral bioavailability (BA) between cynomolgus monkeys and humans, the contributions of first-pass metabolism and intestinal absorption were investigated. Typical substrates of cytochrome P450 enzymes, UDP-glucuronosyltransferase enzym