Species differences in the effects of prostanoids on MAP kinase phosphorylation, myosin light chain phosphorylation and contraction in bovine and cat iris sphincter smooth muscle
โ Scribed by I. Kaddour-Djebbar; H.R. Ansari; R.A. Akhtar; A.A. Abdel-Latif
- Book ID
- 116838327
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 416 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0952-3278
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
There is general agreement now that elevation of intracellular calcium ion concentration [( Ca2+]i) mediates the physiological actions of a number of hormones, neurotransmitters and other pharmacological agents. In smooth muscle one way by which these agents elevate [Ca2+]i and induce contraction in
Biochemical studies have shown that wortmannin is an inhibitor of myosin light chain (MLC) kinase (Nakanishi et al. (1992) J. Biol. Chem. 267: 2157-2163). To investigate the role of MLC kinase in smooth muscle contractions, we examined the effects of wortmannin on isolated smooth muscles of the rat