The present study concerns the percutaneous absorption of naproxen (NPX), as model anti-inflammatory drug, included in liposome formulations constituted of different lipids: stratum corneum lipids (SCL) and phosphatidylcholine/cholesterol (PC/CHOL). Liposome dispersions were produced using two diffe
Species differences in percutaneous absorption of nicorandil
β Scribed by Kiyoshi Sato; Kenji Sugibayashi; Yasunori Morimoto
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 663 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0022-3549
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The percutaneous absorption and disposition of iodochlorhydroxyquin (5-chloro-7-iodo-8-quinolinol; I) from a 3% cream were studied in five dogs over a 28-d topical treatment period. Plasma levels, determined by HPLC, were 0.275-0.525 microgram/mL. The steady-state elimination rate of total I in urin