Species differences in mutagenicity testing: I. Micronucleus and SCE tests in rats, mice, and Chinese hamsters with aflatoxin B1

Coumarin chemoprotection against aflatox

Coumarin chemoprotection against aflatoxin B1-induced gene mutation in a mammalian cell system: A species difference in mutagen activation and protection with chick embryo and rat liver S9

✍ Douglas E. Goeger; Karl E. Anderson; Abraham W. Hsie 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 198 KB

Coumarin (1,2-benzopyrone), a natural food con-nicity with rat liver S9. When liver S9 from chick stituent, prevents polycyclic aromatic hydrocarbon-embryos pretreated with coumarin was used for aflainduced neoplasms in rats and mice, but has not toxin B 1 bioactivation, mutant frequency and cytotox