Species Difference among Experimental Rodents in the Activity and Induction of Cytochrome P-450 Isozymes for Mutagenic Activation of Carcinogenic Aromatic Amines

Expression of cytochromes P450 and gluta

Expression of cytochromes P450 and glutathione S-transferases in human prostate, and the potential for activation of heterocyclic amine carcinogens via acetyl-coA-, PAPS- and ATP-dependent pathways

✍ Oscar A. Di Paolo; Candee H. Teitel; Susan Nowell; Brian F. Coles; Fred F. Kadlu 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 170 KB 👁 1 views

Dietary factors appear to be involved in the high incidence of prostate cancer in "Westernized" countries, implicating dietary carcinogens such as heterocyclic amines (HAs) in the initiation of prostate carcinogenesis. We examined 24 human prostate samples with respect to their potential for activat