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Specialised adaptors in immune cells

✍ Scribed by André Veillette

Book ID: 113524565
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 231 KB
Volume: 16
Category: Article
ISSN: 0955-0674
DOI: 10.1016/j.ceb.2004.01.002

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By mediating non-covalent protein-protein interactions, adaptors organize and assemble the multimolecular signalling complexes that coordinate intracellular programs leading to the activation and differentiation of lymphocytes. The co-ordinated interaction between adaptor and effector molecules is r