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Spatial working memory deficits in GluA1 AMPA receptor subunit knockout mice reflect impaired short-term habituation: Evidence for Wagner's dual-process memory model

✍ Scribed by David J. Sanderson; Stephen B. McHugh; Mark A. Good; Rolf Sprengel; Peter H. Seeburg; J. Nicholas P. Rawlins; David M. Bannerman

Book ID: 113819977
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 715 KB
Volume: 48
Category: Article
ISSN: 0028-3932
DOI: 10.1016/j.neuropsychologia.2010.03.018

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Spatial alternation, win-shift behavior has been claimed to be a test of working memory in rodents that requires active maintenance of relevant, trial-specific information. In this review, we describe work with GluA1 AMPA receptor subunit knockout mice that show impaired spatial alternation, but nor