Spatial structure of β-substituted alkoxyvinyl trifluoromethyl ketones
✍ Scribed by Sergey I. Vdovenko; Igor I. Gerus; Natalia V. Lutenko; Valery P. Kukhar; Jacek Wójcik
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 185 KB
- Volume
- 840
- Category
- Article
- ISSN
- 0022-2860
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## Abstract The reaction of a series of β‐methoxyvinyl trifluoromethyl ketones [CF~3~COC(R^2^)C(OMe)R^1^, where R^1^ = Me, ‐(CH~2~)~3~‐__C__3, ‐CH~2~)~4~‐__C__3, Ph and R^2^ = H, Me, ‐(CH~2~)~3~‐__C__4, ‐(CH~2~)~4~‐__C__4] with __N__‐methylhydroxylamine is reported. The regiochemistry of the react
AbstractÐThe 1,2-and 1.4-addition reactions of trimethylsilyl cyanide to alkyl vinyl ketones were studied. Regioselectivity of this reaction depends on the structure of alkyl vinyl ketones, the reaction temperature and the nature of catalyst. The presence of alkoxy group in b-position of a,b-enone i