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Spatial patterns of α-synuclein positive glial cytoplasmic inclusions in multiple system atrophy

✍ Scribed by Richard A. Armstrong; Peter L. Lantos; Nigel J. Cairns

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 62 KB
Volume: 19
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.10637

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✦ Synopsis

Abstract

In cases of multiple system atrophy (MSA), glial cytoplasmic inclusions (GCI) were distributed randomly or present in large diffuse clusters (>1,600 μm in diameter) in most areas studied. These spatial patterns contrast with those reported for filamentous neuronal inclusions in the tauopathies and α‐synucleinopathies. © 2003 Movement Disorder Society

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