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Spatial Orientation and Dynamics of the U1A Proteins in the U1A−UTR Complex †

✍ Scribed by Clerte, Caroline; Hall, Kathleen B.

Book ID
126971926
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
130 KB
Volume
39
Category
Article
ISSN
0006-2960

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## Abstract The U1A (or nRNP A) protein is known to play a critical role in eukaryotic pre‐mRNA splicing and polyadenylation. Previous studies revealed that several mouse monoclonal antibodies (MAbs) recognized U1A as part of the U1snRNP, while MAb 12E12 was unique in that it recognized an epitope