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Spatial learning deficit in the rat after exposure to a 60 Hz magnetic field

✍ Scribed by Henry Lai

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 264 KB
Volume: 17
Category: Article
ISSN: 0197-8462
DOI: 10.1002/(sici)1521-186x(1996)17:6<494::aid-bem9>3.0.co;2-z

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✦ Synopsis

Rats were trained in ten daily sessions to perform in a 12-arm radial maze, which is a behavioral test for spatial memory functions. Exposure to a 60 Hz magnetic field (45 min, 0.75 mT) immediately before each training session retarded learning significantly. Pretreatment with the cholinergic agonist physostigmine before magnetic field exposure reversed the field's effect on spatial learning. Data from this experiment indicate that magnetic field-induced spatial learning deficit is caused by the effect of the field on cholinergic systems. o 1996 Wiley-l.iss, Inc.

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