Spatial distribution patterns of interphase centromeres during retinoic acid-induced differentiation of promyelocytic leukemia cells

Interferons induce normal and aberrant r

Interferons induce normal and aberrant retinoic-acid receptors type α in acute promyelocytic leukemia cells: Potentiation of the induction of retinoid-dependent differentiation markers

✍ Maurizio Gianní; Stefania Zanotta; Mineko Terao; Alessandro Rambaldi; Enrico Gar 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 978 KB

Treatment of the acute promyelocytic (APL) cell line NB4 with interferon alpha (IFN(alpha)), as well as IFN(beta) and gamma, results in an increased expression of the transcripts coding for retinoic-acid receptor type alpha (RAR(alpha)) and the leukemia-specific retinoic acid receptor PML-RAR. Trans