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Spatial discrimination deficits by excitotoxic lesions in the Morris water escape task

✍ Scribed by L. Spowart-Manning; F.J. van der Staay

Book ID: 116283704
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 136 KB
Volume: 156
Category: Article
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2004.05.031

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## Abstract Symptoms in the early stages of Huntington's disease (HD) are assumed to reflect basal ganglia circuit dysfunction secondary to degeneration of striatal projections to the external segment of the globus pallidus (GPe). The hypothesis that GPe lesion would ameliorate HD symptoms by “norm