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Sp1 Upregulates Survivin Expression in Adenocarcinoma of Lung Cell Line A549

✍ Scribed by Yuqing Chen; Xiaojing Wang; Wei Li; Hailong Zhang; Chengling Zhao; Yan Li; Zhenhuan Wang; Changjie Chen

Publisher
Wiley (John Wiley & Sons)
Year
2011
Tongue
English
Weight
265 KB
Volume
294
Category
Article
ISSN
1932-8486

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## Abstract Salvicine is a diterpenoid quinone derived from a traditional Chinese medication that has been shown to possess potent __in vitro__ and __in vivo__ antitumor effects. This compound, which inhibits the activity of Topoisomerase II, was found to equipotently kill various multidrug‐resista