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Sp1 polymorphism in collagen I α1 gene is associated with osteoporosis in lumbar spine of Mexican women

✍ Scribed by Edith Falcón-Ramírez; Leonora Casas-Avila; Antonio Miranda; Pilar Diez; Clementina Castro; Julieta Rubio; Rocío Gómez; Margarita Valdés-Flores

Publisher
Springer
Year
2010
Tongue
English
Weight
274 KB
Volume
38
Category
Article
ISSN
0301-4851

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## Abstract ## Objective A common G/T substitution at an Sp1 binding site in intron 1 of the COL1A1 gene has been reported to be associated with reduced bone mineral density and increased risk of osteoporotic fracture. The purpose of this study was to examine whether there is an association betwee