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Sp1 mediate hypoxia induced ephrinB2 expression via a hypoxia-inducible factor independent mechanism

✍ Scribed by Marcus Sohl; Fredrik Lanner; Filip Farnebo

Book ID
116299414
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
396 KB
Volume
391
Category
Article
ISSN
0006-291X

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## Abstract Sleep‐disordered breathing with recurrent apnea is associated with intermittent hypoxia (IH). Cardiovascular morbidities caused by IH are triggered by increased generation of reactive oxygen species (ROS) by pro‐oxidant enzymes, especially NADPH oxidase‐2 (Nox2). Previous studies showed