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Sp transcription factor family and its role in cancer

โœ Scribed by Stephen Safe; Maen Abdelrahim

Book ID
116428715
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
289 KB
Volume
41
Category
Article
ISSN
0959-8049

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โœ Adrian R. Black; Jennifer D. Black; Jane Azizkhan-Clifford ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 232 KB

## Abstract The Sp/KLF family contains at least twenty identified members which include Sp1โ€4 and numerous krรผppelโ€like factors. Members of the family bind with varying affinities to sequences designated as โ€˜Sp1 sitesโ€™ (e.g., GCโ€boxes, CACCCโ€boxes, and basic transcription elements). Family members