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SP-A1, SP-A2 and SP-D gene polymorphisms in severe acute respiratory syncytial infection in Chilean infants

✍ Scribed by Sandra Ampuero; Vivian Luchsinger; Lorena Tapia; María Angélica Palomino; Carmen E. Larrañaga

Book ID: 104050834
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 772 KB
Volume: 11
Category: Article
ISSN: 1567-1348
DOI: 10.1016/j.meegid.2011.04.033

No coin nor oath required. For personal study only.

✦ Synopsis

Respiratory syncytial virus (RSV) is the principal pathogen that causes acute lower respiratory tract infection (ALRI) in infants. Severe RSV-ALRI has been associated with the host genetic susceptibility. To assess whether severe RSV disease in infants is associated with certain single nucleotide polymorphism (SNP) into the gene of SP-A1, SP-A2 and SP-D, a prospective study was performed among blood donors and RSV-infected infants aged

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